Francisco Bustamante (c.1680–1737) was a Spanish painter.
Bustamante was born at Oviedo, and studied painting with Miguel Jacinto Menendez at Madrid. On the ceiling of the sacristy of Oviedo Cathedral he painted a fresco representing 'The Assumption of the Blessed Virgin,' from a sketch sent from Rome; also a series for the cloister of the Franciscans. He excelled in portraiture; his likenesses, executed with fidelity and skill, are to be met with in the best houses of the Asturias. He died in Oviedo.
This article incorporates text from the article "BUSTAMANTE, Francisco" in Bryan's Dictionary of Painters and Engravers by Michael Bryan, edited by Robert Edmund Graves and Sir Walter Armstrong, an 1886–1889 publication now in the public domain.